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    <loc>https://www.cm-dx.com/news-and-resources/samples-that-interfere-with-endotoxin-assays-a-modern-dilemma</loc>
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      <image:title>News and Resources - Samples that interfere with endotoxin assays: a modern dilemma - Make it stand out</image:title>
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      <image:title>News and Resources - Samples that interfere with endotoxin assays: a modern dilemma - Make it stand out</image:title>
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      <image:title>News and Resources - Samples that interfere with endotoxin assays: a modern dilemma - Make it stand out</image:title>
      <image:caption>Figure 1. Interrelationship between endotoxin limit, sample dilution and limit of detection. When the endotoxin limit for a product is 0.1 Eu/mL or less sample dilution rapidly becomes impractical as a method for reducing assay interferences. (LoD = Limit of detection; LoQ = Limit of quantitation).</image:caption>
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      <image:title>News and Resources - Samples that interfere with endotoxin assays: a modern dilemma - Make it stand out</image:title>
      <image:caption>Figure 2. All samples in this figure have been successfully tested for endotoxin using αBET™ with Fujifilm Biosciences’ Pyrostar turbidimetric LAL reagent. Samples are either undiluted or diluted by 1/10. (i) gold nanoparticles of a various sizes; (ii) pNA of various dilutions; (iii) undiluted cell culture media; (iv) horse serum; (v) phenol blue ophthalmic solutions; (vi) mammalian cell suspension containing 5 x 106 cells/mL</image:caption>
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      <image:title>News and Resources - Low-Endotoxin Recovery (LER) in Biopharmaceutical Products - Make it stand out</image:title>
      <image:caption>Figure 1 shows a range of possible endotoxin masking-time profiles resulting from the addition of an endotoxin spike on day 0. Notice that not only does the maximum degree of masking vary but the time it takes to achieve this maximum level also varies. A range of widely varying profiles can be encountered, and indeed the time axis in figure 1 may span multiple days.</image:caption>
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      <image:caption>Table I – Summary comparison of CMD’s αBET™ and the market-leading cartridge systems, covering cost, operational design, regulatory compliance, analytical flexibility, specificity, and robustness in complex matrices.</image:caption>
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      <image:caption>*KTA = Kinetic Turbidimetric Assay; KCA = Kinetic Chromogenic Assay</image:caption>
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      <image:caption>Figure 1 – Results of the River Taff Study: endotoxin concentration in samples collected along the river's course.</image:caption>
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