Introducing the αBET System
A fully integrated endotoxin testing system that delivers best-in-class sensitivity using a fraction of FDA-licensed turbidimetric LAL reagent.
Introducing the αBET® System
In collaboration with FUJIFILM Wako Chemicals U.S.A. Corporation
We’re proud to bring you a fully integrated testing system providing a more rapid and sustainable solution to endotoxin testing without compromising on sensitivity or performance.
Revolutionise your endotoxin testing
Market-leading performance using <10% of turbidimetric LAL reagent
Quantitative results delivered in half the time of traditional tests
System walks users through performing a pharmacopoeial compliant assay or allows flexible sample analysis
On-board FDA part 11 ready software ensures data integrity
Rapid, cost-effective, compliant testing at point-of-need
Find the right support for your endotoxin testing needs
Different organisations require different levels of support. Whether you are implementing endotoxin testing for the first time, working within a defined budget or requiring accredited results for release, our service adapts to your regulatory and operational needs.
Testing Complex & Biopharma Products
Biologics, nanoparticles formulations, coloured solutions and light-scattering matrices can challenge conventional turbidimetric or chromogenic systems.
αBET® utilises a proprietary magneto-optical detection principle that is more tolerant of coloured and hazy samples, while maintaining pharmacopoeial compliance and robust spike recovery performance.
In-Process Control & Manufacturing Monitoring
Routine endotoxin monitoring during upstream and downstream processing significantly reduces the risk of late-stage OOS failures, batch rejection and costly production delays.
αBET® provides results in minutes (<6 mins at 1 EU/mL; <11 mins at 0.1 EU/mL) with simplified workflow and lower per-test cost, enabling practical implementation of in-process testing where traditional methods have been prohibitive.
Healthcare Water & Conventional Pharma
From purified water and WFI monitoring to routine testing of small-molecule injectables, αBET® delivers quantitative results across 0.001–10 EU/mL using a single FDA-licensed lysate, simplifying inventory control and reagent qualification requirements.
Using FUJIFILM Wako’s Pyrostar™ ES-F reagent, the system avoids cross-reactivity with (1,3)-β-D-glucans and supports fully compliant pharmacopoeial assays.
Cost-Effective Cartridge-Based Testing
αBET® delivers the convenience of a cartridge-based workflow while reducing lysate consumption by >90% and lowering recurrent per-test cost to approximately one third of other cartridge systems, supporting long-term operational cost control.
A single consumable and reagent combination supports multiple test modes, eliminating the need for multiple cartridge sensitivities.
“We have rapidly integrated the AlphaBET into our routine QC validation for all of our R&D products. We are very happy with the instrument, and it has saved us thousands of dollars on external tests and weeks of sample transit time. One aspect that we really appreciate is how much simpler it is to perform a LAL quantification, compared to a standard chromogenic assay. As a small company, not needing to buy a spectrophotometer just to perform LAL assays was really a dealbreaker towards acquiring the AlphaBET”
- Vincent-Daniel Girard, Vice-président / CSO of AxCell Labs, CanadaαBET® Expansion Module (EM)
New!
For laboratories requiring higher throughput, the αBET® Expansion Module extends the core system without altering validated workflows or assay performance.
The Expansion Module connects directly to the αBET® Master system, enabling two cartridges to run simultaneously in true random-access mode. This effectively doubles testing capacity while preserving the same sensitivity, time-to-result and regulatory compliance delivered by the base system.
Designed for seamless integration, the Expansion Module uses the same consumables, reagents and software environment as the αBET® system. Users benefit from increased productivity without additional training, method redevelopment or changes to established SOPs.
A one-stop shop for all endotoxin testing needs
Cotton Mouton Diagnostics Ltd (CMD) operates under an ISO 9001 Quality Management System certified by BSI under certificate number FS749484, covering the manufacture and assembly of the αBET® System and our endotoxin testing service.
We are also a UKAS accredited testing laboratory No. 23137 for our endotoxin testing service, ensuring precision, reliability, and full regulatory compliance.