Introducing the αBET System
A fully integrated endotoxin testing system that delivers best-in-class sensitivity using a fraction of FDA-licensed turbidimetric LAL reagent.
Introducing the αBET® System
In collaboration with FUJIFILM Wako Chemicals U.S.A. Corporation
We’re proud to bring you a fully integrated testing system providing a more rapid and sustainable solution to endotoxin testing without compromising on sensitivity or performance.
Revolutionise your endotoxin testing
Market-leading performance using <10% of turbidimetric LAL reagent
Quantitative results delivered in half the time of traditional tests
System walks users through performing a pharmacopoeial compliant assay or allows flexible sample analysis
On-board FDA part 11 ready software ensures data integrity
Rapid, cost-effective, compliant testing at point-of-need
Find the right support for your endotoxin testing needs
Different organisations require different levels of support. Whether you are implementing endotoxin testing for the first time, working within a defined budget or requiring accredited results for release, our service adapts to your regulatory and operational needs.
Testing Complex & Biopharma Products
Biologics, nanoparticles formulations, coloured solutions and light-scattering matrices can challenge conventional turbidimetric or chromogenic systems.
αBET® utilises a proprietary magneto-optical detection principle that is more tolerant of coloured and hazy samples, while maintaining pharmacopoeial compliance and robust spike recovery performance.
In-Process Control & Manufacturing Monitoring
Routine endotoxin monitoring during upstream and downstream processing significantly reduces the risk of late-stage OOS failures, batch rejection and costly production delays.
αBET® provides results in minutes (<6 mins at 1 EU/mL; <11 mins at 0.1 EU/mL) with simplified workflow and lower per-test cost, enabling practical implementation of in-process testing where traditional methods have been prohibitive.
Healthcare Water & Conventional Pharma
From purified water and WFI monitoring to routine testing of small-molecule injectables, αBET® delivers quantitative results across 0.001–10 EU/mL using a single FDA-licensed lysate, simplifying inventory control and reagent qualification requirements.
Using FUJIFILM Wako’s Pyrostar™ ES-F reagent, the system avoids cross-reactivity with (1,3)-β-D-glucans and supports fully compliant pharmacopoeial assays.
Cost-Effective Cartridge-Based Testing
αBET® delivers the convenience of a cartridge-based workflow while reducing lysate consumption by >90% and lowering recurrent per-test cost to approximately one third of other cartridge systems, supporting long-term operational cost control.
A single consumable and reagent combination supports multiple test modes, eliminating the need for multiple cartridge sensitivities.
How does αBET® compare with
conventional cartridge-based testing?
Rapid cartridge testing is convenient, but not all cartridge-based workflows offer the same flexibility, cost or control.
* Based on CMD benchmarking against a leading cartridge-based endotoxin testing system. Cost comparison is based on consumables required for testing; actual costs depend on testing volume and configuration.
More flexibility from a single testing platform
αBET® combines the convenience of cartridge-based testing with greater flexibility over sensitivity range, assay set-up and sample type — while significantly reducing recurrent consumable costs.
“We have rapidly integrated the AlphaBET into our routine QC validation for all of our R&D products. We are very happy with the instrument, and it has saved us thousands of dollars on external tests and weeks of sample transit time. One aspect that we really appreciate is how much simpler it is to perform a LAL quantification, compared to a standard chromogenic assay. As a small company, not needing to buy a spectrophotometer just to perform LAL assays was really a dealbreaker towards acquiring the AlphaBET”
- Vincent-Daniel Girard, Vice-président / CSO of AxCell Labs, CanadaαBET® Expansion Module (EM)
New!
For laboratories requiring higher throughput, the αBET® Expansion Module extends the core system without altering validated workflows or assay performance.
The Expansion Module connects directly to the αBET® Master system, enabling two cartridges to run simultaneously in true random-access mode. This effectively doubles testing capacity while preserving the same sensitivity, time-to-result and regulatory compliance delivered by the base system.
Designed for seamless integration, the Expansion Module uses the same consumables, reagents and software environment as the αBET® system. Users benefit from increased productivity without additional training, method redevelopment or changes to established SOPs.
See how αBET® works in your lab before you commit
From your first conversation to installation and training, CMD supports you through the entire process, including the opportunity to trial αBET® at your own site.
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Tell us what you need
We review your testing volumes, specifications, timelines, regulatory requirements and current workflow.
Timing: 1–7 days
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Get the right αBET® set-up
CMD recommends the most appropriate system configuration and provides a tailored quotation based on your requirements and testing volumes.
Within 7 days of first contact
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Test αBET® in your own laboratory
We can demonstrate the system at your site and, where appropriate, leave it with your team for up to two weeks so you can evaluate the workflow yourself.
Have a challenging product? CMD can also assess your samples before you purchase.
Sample assessment: 8–10 working days
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From order to operation
Once your order is placed, standard instrument lead time is less than two weeks.
CMD provides IQ/OQ, user training and SOP support to help integrate αBET® into your testing workflow.
Installation and training: 1 day
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Expertise beyond installation
CMD remains available for ongoing technical support, troubleshooting and specialist endotoxin testing expertise as your requirements evolve.
Ready to see whether αBET® fits your laboratory?
A one-stop shop for all endotoxin testing needs
Cotton Mouton Diagnostics Ltd (CMD) operates under an ISO 9001 Quality Management System certified by BSI under certificate number FS749484, covering the manufacture and assembly of the αBET® System and our endotoxin testing service.
We are also a UKAS accredited testing laboratory No. 23137 for our endotoxin testing service, ensuring precision, reliability, and full regulatory compliance.