Cost-effective cartridge-based endotoxin testing
Rapid, flexible testing with lower recurrent costs.
Make routine cartridge testing more economical
Cartridge systems can simplify endotoxin testing, but consumable costs and restrictive assay formats can become significant as testing volumes increase.
αBET® combines a straightforward cartridge workflow with greater analytical flexibility and recurrent costs typically around one-third of other cartridge-based systems.
Where conventional cartridge testing
adds cost and complexity
-
Cartridge expenditure increases with every sample tested. For laboratories carrying out frequent quality control or in-process monitoring, the cost per test can quickly outweigh the convenience of the system.
-
Some systems require laboratories to purchase different cartridges for different detection ranges. This increases inventory requirements and creates a risk of unused or expired stock.
-
Pre-configured cartridges may restrict the available sensitivity, calibration approach or sample volume. Laboratories can therefore find themselves adapting their testing strategy to the consumable rather than to the application.
-
When each test is expensive, teams may test only at essential control points. This can reduce opportunities to detect endotoxin contamination earlier in development or manufacturing.
How αBET™ changes the economics of cartridge-based testing
αBET™ combines the operational convenience of a cartridge system with the flexibility of a laboratory-based kinetic assay.
A single consumable and reagent combination supports quantitative testing across 0.001–10 EU/mL, removing the need to purchase different cartridge sensitivities. The system also uses more than 90% less lysate than many conventional testing workflows.
Around one-third
Typical recurrent cost compared with other cartridge systemsMore than 90% less lysate
Reduced reagent consumption per test0.001–10 EU/mL
One consumable across the full quantitative rangeResults in minutes
Typically under 6 minutes at 1 EU/mL and under 30 minutes at 0.001 EU/mL
The αBET™ performance data also demonstrates accuracy and precision comparable with an established tube-reader assay, with substantially shorter time to result.
Where cost-effective cartridge testing matters most
High-frequency routine quality control
When laboratories run repeated tests every week or every day, even a modest difference in consumable price becomes significant.
αBET™ helps reduce the recurrent cost of routine product, raw-material and water testing without replacing the convenience of a cartridge workflow.
Point-of-need and decentralised testing
Teams should not always need to wait for a central laboratory or external testing provider before making an operational decision.
The compact, integrated αBET™ System supports quantitative testing close to the manufacturing, development or healthcare workflow where results are required.
In-process manufacturing monitoring
Cost and turnaround can prevent manufacturers from testing as frequently as they would like during upstream and downstream processing.
Rapid, lower-cost testing makes it more practical to monitor endotoxin at additional process stages and identify contamination before it affects a high-value batch.
Laboratories establishing or expanding in-house capacity
Growing organisations may need faster turnaround and greater control but remain sensitive to capital, consumable and training costs.
A single cartridge strategy simplifies purchasing, inventory management and method implementation as test volumes increase.
Lower cost without compromising analytical control
Cost-effective testing should still provide the traceability, flexibility and data integrity required within a controlled laboratory environment.
αBET™ supports several testing modes:
Pharmacopoeial-compliant testing
The system guides operators through calibration and sample analysis to support a pharmacopoeial-compliant assay.
Calibrated testing
An archived calibration can be selected when rapid quantitative results are required and the approved workflow permits its use.
Non-calibrated testing
Samples can also be assessed without a calibration where relative reaction-time data are appropriate.
On-board FDA 21 CFR Part 11-ready software supports controlled user access, real-time data visualisation, archived records and structured reporting.
When αBET™ may be the right fit for your operation
Consider αBET® when:
recurring cartridge costs are limiting how often you test;
your laboratory currently purchases several cartridge sensitivities;
faster in-house results would improve manufacturing or quality decisions;
you require both rapid operational testing and pharmacopoeial-compliant workflows;
reagent consumption and laboratory waste are part of your sustainability objectives;
or your testing volume is increasing and your current model no longer scales economically.
Latest News and Resources
Talk to CMD about your current testing costs
The cost of endotoxin testing depends on more than the instrument purchase price.
CMD can assess your current testing workflow and help determine whether αBET® could reduce recurrent costs.